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You can have multiple sheets with your personalized messages.
Once you have set up all the numbers and their messages all you need to do is cross check to ensure that you have the correct information before you upload.
Your excel file might look like this when you first enter the numbers.

What you should do with this is to right click the first column (A) and select format cells.

You will get the following dialog window.

Choose Custom from Category on the left. And on the right side from Type, choose 0 as in the picture above
That should make all the numbers appear in full as they should be, with the result below.

Now you are ready to upload.
*Also, please ensure that you have enough units in your account to send the message.
This is to ensure that all your messages are processed.